Das Themengebiet der Psychopathie hat in den letzten Jahrzehnten vor allem durch Filme, die sich mit (vermeintlich) psychopathischen Charakteren beschäfti- gen, ein breites gesellschaftliches Interesse erfahren (vgl. Swart 2016). Holly- woods Blockbuster zeigen hier Beispiele hochintelligenter (z. B. Hanibal Lector in „Das Schweigen der Lämmer“) oder sexuell devianter (z. B. Patrick Bateman in „American Psycho“) Serienkiller, welche aus klinischer Sicht tatsächlich hoch psy- chopathische Tendenzen aufweisen. Demgegenüber werden psychisch andersartig beeinträchtigte Filmcharaktere, wie z. B. Norman Bates („Psycho“) oder Travis Bickel (...) („Taxi Driver“) wohl aufgrund ihrer schreckenseinflößenden Wirkung im allgemeinen Sprachgebrauch oft als Psychopathen bezeichnet, obwohl ihre Symptome aus forensisch-psychiatrischer Sicht eher schizoiden Wahnvorstellungen ähneln und keine Anzeichen einer klas- sischen Psychopathie darstellen (vgl. Leistedt / Linkowski 2014). Auch Medienbe- richte über tatsächlich existierende, brutale (z.B. Serienkiller Ted Bundy) oder dreiste (z.B. Anlagebetrüger Bernard Madoff) Figuren der Zeitgeschichte haben die konzeptionelle Unübersichtlichkeit des in der Öffentlichkeit wahrgenommenen Bildes der Psychopathie befeuert. Und sogar in medizinischen bzw. psychiatri- schen Kreisen scheint eine uneinheitliche Sichtweise die Konfusion um das Stö- rungsbild Psychopathie weiter anzufachen (vgl. Berg et al. 2013). (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Should Marxists support universal basic income (UBI), i.e., a regular cash income paid to all without a means test or work requirement? This paper considers one important argument that they should, namely that UBI would be instrumentally effective in helping to bring about communism. It argues that previous answers to this question have paid insufficient attention to a logically prior question: what is Marx’s account of communism? In reply, it distinguishes two different accounts: a left-libertarian version that associates communism with (...) the freedom to live and work how one wants, and a perfectionist version that associates communism with the overcoming of alienated labour and self-realisation in work. It argues that UBI would make steps towards the left-libertarian account but not the perfectionist account. Ultimately, then, the question “should Marxists support basic income?” is shown to partly depend on which account of communism Marxists want to bring about. (shrink)

This paper provides an analysis of the intrinsic/extrinsic distinction, as applied both to properties and to relations. In contrast to other accounts, the approach taken here locates the source of a property’s intrinsicality or extrinsicality in the manner in which that property is ‘logically constituted’, and thus – plausibly – in its nature or essence, rather than in e.g. its modal profile. Another respect in which the present proposal differs from many extant analyses lies in the fact that it does (...) not seek to analyse the ‘global’ distinction between intrinsic and extrinsic properties on the basis of the ‘local’ distinction between having a property intrinsically and having it extrinsically. Instead, the latter distinction is explicated on the basis of the former. (shrink)

The development of nuclear energy technologies in the second half of the 20th century came with great hopes of rebuilding nations recovering from the devasta-tion of the Second World War or recently released from colonial rule. In coun-tries like France, India, the USA, Canada, Russia, and the United Kingdom, nuclear energy became the symbol of development towards a modern and technologically advanced future. However, after more than six decades of experi-ence with nuclear energy production, and in the aftermath of the (...) Fukushima nuclear disaster, it is safe to say that nuclear energy production is not without its problems.Some of these problems have their origins in the very materiality of the technolo-gies involved. For example, not only does the use of highly radioactive materials give rise to risks for the current generation (e.g., in the potential for disaster when reactors melt down) but high-level radioactive waste from nuclear energy production presents a serious intergenerational problem for which an acceptable final solution or its implementation remains elusive. Moreover, nuclear energy technologies have specific social and political consequences. For example, they have been said to be authoritarian technologies (Winner, 1980), requiring cen-tralized authority, secrecy, and technocratic decision-making. While some of these problems could have been foreseen before nuclear energy technologies were introduced, others only arose after these technologies were already integrated into the social and infrastructural fabric of our lives. Addition-ally, new technologies (e.g., Generation III, III+ and IV reactors) are still being developed, bringing with them new and uncertain hazards and risks. Ignorance and uncertainty about the possible deleterious effects of introducing a new technology are inevitable, especially if the technology is complex, large time-scales are involved, or risks depend on social or political factors unforeseen in the design stage. However, this should not deter us from developing and intro-ducing new technologies. Rather, it should motivate us to organize these ‘exper-iments’ with new technologies in society in such a way that we can learn about their possible hazards and risks as effectively and responsibly as possible (van de Poel, 2011, 2015). In this way, it is possible to minimize risks and avoid unwant-ed moral, social or political developments. However, organizing such experi-ments responsibly also means that one could come to the conclusion that continuing an experiment is no longer responsible or desirable. Should we be prepared for such a scenario, and if so, how could we do that? One possible strategy to tackle this issue is that the technology and its introduction should be reversible. The aim of this thesis is to further explore this strategy by answering the following main research question (RQ) and accompanying subquestions (SQ):RQ: What are the implications of reversibility for the responsible develop-ment and implementation of nuclear energy technologies?SQ1: Under what conditions can nuclear energy technologies be considered reversible?SQ2: Why should nuclear energy technologies be reversible?SQ3: If so, how could the reversibility of nuclear energy technologies be achieved?After the introductory chapter 1, the chapters that form the main body of this dissertation each provide a distinct contribution to answering the three subques-tions and, by extension, the main research question. Guided by three historical case studies of nuclear energy technology development (i.e., India, France and the USA), chapter 2 answers the first subquestion by formulating the two condi-tions under which it can be considered reversible, i.e., 1) the ability to stop the further development and deployment of a that technology in society, and 2) the ability to undo the undesirable outcomes (material, institutional or symbolic) of the development and deployment of the technology. Chapter 3 subsequently tackles the second subquestion by establishing the general desirability of technological reversibility by virtue of its relation to responsibility in Emmanuel Levinas’ ethical phenomenology. It argues that technology development is a legitimate response to responsibility but inevitably falls short of the responsibility that inspires it, incessantly calling for technological and political change in the process. Having thus argued that nuclear energy technologies should ideally be reversible, chap-ters 4 and 5 work towards specific strategies to achieve technological reversibil-ity. Chapter 4 first investigates the processes that make it difficult to stop the further development and implementation of a nuclear energy technology in society, thus provid-ing input on how to fulfill the first condition for the reversibility of nuclear energy technologies. To do so, it presents a phenomenological perspective on technology and its adoption based on the work of Alfred Schutz. It also explores different ways in which technology adoption drives the processes of path depend-ence towards technological lock-in. Chapter 5 examines the history of geological disposal of high-level radioactive waste in the USA. It identifies a number of concrete policy pitfalls that could lead to lock-in and that should consequently be avoided. It also presents a number of general design strategies that could facilitate the undoing of undesirable consequences of a technology, thus providing input on how to fulfill the second condition for the reversibility of nuclear energy technol-ogies.Chapter 6 summarizes the central findings of the thesis and explains how these help to answer the research questions. On top of this, it reflects on a number of complications connected to reversibility considerations. Based on this, it is concluded that the question of irreversibility and reversibility is context- and technology-specific and a matter of degree. The chapter concludes with a reflec-tion on generalizations and limitations of the results. Finally, chapter 7 discusses the implications of this dissertation’s results for responsibly experimenting with nuclear energy technologies in society. (shrink)

Why are conditional degrees of belief in an observation E, given a statistical hypothesis H, aligned with the objective probabilities expressed by H? After showing that standard replies are not satisfactory, I develop a suppositional analysis of conditional degree of belief, transferring Ramsey’s classical proposal to statistical inference. The analysis saves the alignment, explains the role of chance-credence coordination, and rebuts the charge of arbitrary assessment of evidence in Bayesian inference. Finally, I explore the implications of this analysis for Bayesian (...) reasoning with idealized models in science. (shrink)

The semantic view on theories has been much in vogue over four decades as the successor of the syntactic view. In the present paper, I take issue with this approach by arguing that theories and models must be separated and that a theory should be considered to be a linguistic systems consisting of a vocabulary and a set of rules for the use of that vocabulary.

In his 1953 lectures at the College de France, Merleau-Ponty dedicated much effort to further developing his idea of embodied subject and interpreted fresh sources that he did not use in Phenomenology of Perception. Notably, he studied more in depth the neurological notion of "body schema". According to Merleau-Ponty, the body schema is a practical diagram of our relationships to the world, an action-based norm with reference to which things make sense. Merleau-Ponty more precisely tried to describe the fundamentally dynamic (...) unity of the body, i.e. the fact there are various possibilities how the practical "diagram" of body schema could be de-differentiated (in pathology) or further refined (via cognitive and cultural superstructures, symbolic systems). This chapter summarises Merleau-Ponty's interpretation of the notion, while contrasting it to the more traditional understanding of the body in phenomenology and recent philosophical texts dealing with body schema. (shrink)

The paper aims to define the concept of “felt sense”, introduced in psychology and psychotherapy by E. T. Gendlin, in order to clarify its relation to bodily sensations and its difference from emotions. Gendlin’s own definition, according to which the felt sense is a conceptually vague bodily feeling with implicit meaning, is too general for this task. Gendlin’s definition is specified by pointing out, first, the different layers of awareness of bodily feelings and, second, the difference between bodily readiness for (...) action and motivation for action. According to the more precise definition, the felt sense is the awareness of readiness to act carried by the configuration of bodily sensations. The felt sense differs from emotions because it is not able to motivate the action for which it makes us ready. The article also discusses the intuition that led to the founding of Gendlin’s psychotherapeutic technique and compares it with the psychoanalytic concept of working through resistance during therapy. (shrink)

This paper presents an account of what it is for a property or relation (or ‘attribute’ for short) to be logically simple. Based on this account, it is shown, among other things, that the logically simple attributes are in at least one important way sparse. This in turn lends support to the view that the concept of a logically simple attribute can be regarded as a promising substitute for Lewis’s concept of a perfectly natural attribute. At least in part, the (...) advantage of using the former concept lies in the fact that it is amenable to analysis, where that analysis—i.e., the account put forward in this paper—requires the adoption neither of an Armstrongian theory of universals nor of a primitive notion of naturalness, fundamentality, or grounding. (shrink)

In a recent paper Horsten embarked on a journey along the limits of the domain of the unknowable. Rather than knowability simpliciter, he considered a priori knowability, and by the latter he meant absolute provability, i.e. provability that is not relativized to a formal system. He presented an argument for the conclusion that it is not absolutely provable that there is a natural number of which it is true but absolutely unprovable that it has a certain property. The argument depends (...) on a description principle. I will argue that the latter principle implies the knowability of all arithmetical truths. Therefore, Horsten's argument is either sound but its conclusion is trivial, or his argument is unsound. (shrink)

The aim of this chapter is to show how we can account for a most peculiar feature of human life: i.e. the need to address the real possibility of failing to be ourselves.

Abstract:We analyzed co-citation patterns in 332,498 articles published in Anglophone psychology journals between 1946 and 1990 to estimate (1) when cognitive psychology first emerged as a clearly delineated subdiscipline, (2) how fast it grew, (3) to what extent it replaced other (e.g., behaviorist) approaches to psychology, (4) to what degree it was more appealing to scholars from a younger generation, and (5) whether it was more interdisciplinary than alternative traditions. We detected a major shift in the structure of co-citation networks (...) between approximately 1955 and 1975 and draw novel conclusions about the developments commonly referred to as "the cognitive turn.". (shrink)

The goal of our article is to review the widespread anthropological figure, according to which we can achieve a better understanding of humans by contrasting them with animals. This originally Herderian approach was elaborated by Arnold Gehlen, who characterized humans as “deficient beings” who become complete through culture. According to Gehlen, humans, who are insufficiently equipped by instincts, indirectly stabilize their existence by creating institutions, i.e., complexes of habitual actions. On the other hand, Maurice Merleau-Ponty shows that corporeal relationship to (...) the world is already indirect because it is based on preestablished and readjusted “standards” or “norms” of interaction with the environment. Merleau-Ponty then calls these norms “institutions” and views culture as readjustment of institutions which operate already on the level of corporeal existence. The anthropological figure of confronting humans and animals thus cannot produce, as in Gehlen, a contrast between an allegedly “direct” relationship to the world in animals and a supposedly “indirect” relationship to the world in humans. The Herderian approach can be meaningfully retained only if interpreted as an invitation to confront the norms of indirect interaction with the world in animals and in people, that is, if viewed as a comparison of their respective institutions. (shrink)

The Role of Negation in the Description of the World According to Aristote’s Metaphysics. The notions of ‘being’ and ‘non-being’ have entered philosophical language, forming the basis of ontology and meontology, as the counterparts of the Greek expressions to on and to me on (nominalised forms, affirmative and negative, of the participle of the verb einai). Originally, however, these expressions did not have any objectifying meaning, but played the role of meta-language names, representing the copula einai in all its forms, (...) most generally in its affirmative and negative forms. The copula itself, which in later philosophy took on the existential meaning, had functioned only as a semantically empty connective of predicates. Over time the participle on has been used as a universal name of all predicates. The above-mentioned expressions became central in Greek philosophical terminology thanks to the debates, initiated by Parmenides, on the role of negation in the description of the world. Parmenides himself proposed a complete excision of negative sentences as describing by elimination, and created a positive-monistic system which abandoned multiplicity, divisibility, and variability. Later philosophers defended negation, fighting back against the paradoxes formulated by the Eleatics and later by the Sophists. Plato observed that without negation it is impossible to describe the multiplicity of things. He also distinguished a relative negation which does not eliminate anything but makes it possible to confront some things with others. According to the atomists, the divisibility of physical things forces us to accept that they consist of a positive element in the form of an impenetrable body, and of another element lacking any characteristics, i.e. the void. Finally, Aristotle, when analysing the process of change, justified the consistency of the statement that something comes out of “not being” and “being”, under the assumption that the former is understood as being actual, and the latter as being potential. In all these conceptions there is nothing non-existent, there are only proposals of how to identify the aspects of reality whose explanation justifies the use of negation. The affirmative and negative forms of the above expressions have also provoked reflection on the problem of truth and falsity. It has been observed that they are used in everyday language not only to state an agreement or disagreement with the actual facts of the matter, but also to affirm or deny something. (shrink)

The paper shows different approaches to creativity, i.e. emergence of new meanings, in Merleau-Ponty and Patočka. The comparison is based mainly on Merleau-Ponty’s lectures L’institution dans l’histoire personnelle et publique (1954/55) and Patočka’s project Negative Platonism (1953). Despite some similarities evident in the key concepts “institution” and “transcendence”, there is a decisive difference between the two approaches concerning the temporality of creation. Whereas Merleau-Ponty likens the temporality of institution to future perfect tense, emphasizing the intertwining of present and future events, (...) Patočka understands novelty as something totally different from the present state of affairs. In his eyes, the question of how something new can arise equals the question of how an attitude of distance to existing traditions can be achieved. Contrary to Patočka, Merleau-Ponty argues that any living tradition tends towards its own transformation and presents a case of self-transcendence because it is governed by the principle of divergence (écart). Finally, we argue that some aspects of these two approaches both complement each other, and also show the limits of each other. (shrink)

In this paper I argue that to understand minded agency – the capacity we typically find instantiated in instances of human behaviour that could sensibly be questioned by asking “What did you do?” – one needs to understand childhood, i.e. the trajectory of learning to act. I discuss two different types of trajectory, both of which seem to take place during childhood and both of which might be considered crucial to learning to act: a growth of bodily control (GBC) and (...) a growth in taking responsibility (GTR). The discussion of GTR takes up about half of the entire paper. In the final two sections I argue that GTR is the most promising trajectory in terms of which to understand a child’s process of learning to act. (shrink)

In the novel A Burnout-Out Case, Graham Greene argues for an intimate relationship between burnout and happiness. The novel claims that a life worth living is a continuous balancing between something painful, e.g. burnout and something desirable, e.g. happiness. In this essay, I try to make a case for the happiness of burnout. By examining the case story of a young artist, who suffered from burnout, I describe how such suffering might open up for a necessary reevaluation of the values (...) that actually make sense. Such creation of new values is what eventually leads to more happy moments, not happiness per se. This essay provides a philosophical reflection regarding the relationship between happiness and burnout in order to say something regarding which life is worth living. (shrink)

According to Eugen Fink, a thorough elucidation of the meaning of play has the capacity to lead us towards an understanding of the world as a totality. In order to go beyond Plato’s understanding of play as an inferior copy of serious action, Fink provides an analysis of the cultic game. This form of playing cannot be said to be the origin of all play, but it enables us to demonstrate how the act of playing transcends circumscribed beings inside the (...) world and provides a relationship with a higher whole, in which the community participating in the play is encompassed. A masked shaman does not represent a particular god, but brings to presence the action of gods upon humans as such. Thus, the cultic game is a symbol of a more important reality, not an inferior representation of an individual reality. This, however, is still not a sufficiently radical interpretation of the ontological dimension of play: the whole is only understood as an action of gods, i.e. mediately. Fink strives to demonstrate on the cont... (shrink)

Howard Phillips Lovecraft’s work of fiction can roughly be grouped into three distinct categories, each evoking a singular extraordinary state of mind. Poe-inspired tales of the macabre such as “The Tomb” (1917) and “The Statement of Randolph Carter” (1919) produce terror because of the atmosphere they convey and because of the particular end the main characters meet. Lovecraft’s later “Yog-Sothothery” or work in the Cthulhu Mythos tradition, including his signature pieces of weird fiction “The Call of Cthulhu” (1926) and “The (...) Shadow over Innsmouth” (1931), inspires ‘horror’ because the life-worlds of the protagonists in these stories are utterly destroyed. However, the gentleman of Providence is also known for a different sort of fiction. His Dunsanian tales—among them short stories such as “The White Ship” (1919), “Celephaïs” (1920), and the three works“ The Silver Key” (1926), The Dream-Quest of Unknown Kadath (1926–27), and “Through the Gates of the Silver Key” (1932–33; with E. Hoffmann Price), centered on the exploits of Lovecraft’s recurring character and alter ego Randolph Carter—are epitomes to this feat. These prehistoric or dreamland tales do not inspire ‘terror’ or ‘horror’; rather, they predominately seek to evoke the extraordinary state of mind called ‘wonder. This article offers a preliminary exploration of Lovecraft’s relationship with wonder, highlights what wonder is, how Lovecraft was exposed to wonder at an early age, and argues that he developed a lifelong positive relationship with this particular state of mind. (shrink)

[In Czech] In his writings at the end of the fifties, Merleau-Ponty introduced a new semantic and expressional circuit with the concept of “visibility”, a variation on the concept of “flesh” (chair). The aim of this article is to show that a consistent interpretation of this circuit necessarily leads us to a consideration of the concept of visibility as a systematically privileged viewpoint for the interpretation of all Merleau-Ponty’s more particular discussions. The concept of visibility, or flesh, summarises Merleau-Ponty’s thesis (...) that the proper cohesion of the “horizon” or “field” is prior to that which is objectively and individually thinkable within it. Thus, Merleau-Ponty’s pivotal idea is set down not just from the phenomenological viewpoint, or in particular instances, but rather quite generally and in an ontological sense. The article offers an analysis of the lexis related to the concept of visibility, characterises Merleau-Ponty’s conception of phenomenon from its perspective and summarises its ontological consequences, using the example of two central themes i.e. the the relation between subject and object and the relation between the empirical and ideal. (shrink)

In this essay I consider the end-of-art thesis in its metaphysical and empirical versions. I show that both use the correspondence theory of truth as the basis for their conception of the history of art. As a counterpart to these theories I have chosen Patočka’s conception of the history of art. His theory is based also on the relationship between art and truth, but he conceives truth in the phenomenological sense of manifestation. In the rest of the essay I seek (...) to show the consequences Patočka’s conception has for the history of art. In the rst part, I set out to show Patocka’s critique of Hegel’s aesthetics as a system based on the correspondence theory of truth. In particular, I endeavour to explain his critique of some intrinsic problems of Hegel’s aesthetics, the general failure of Hegel’s system to achieve its goal, and, lastly, Hegel’s giving up on the meaning of the art in the present. I also seek to show that Danto’s version runs into the same problems and conclusions as Hegel’s. In the second part I discuss Patočka’s analysis of modern art and the aesthetic attitude, where he nds a hidden a nity between art and aletheia, which Hegel overlooked. e last part of the essay focuses on the consequences that the conception of the truth of art as aletheia have for the history of art. I conclude that art in such a conception represents an independent eld of the manifestation of being in history beside philosophy. Moreover, modern and contemporary art do not mean the end of art; rather, they have their place in art history based on aletheia, since they are more focused on the manifestation itself than on what is manifested. Unlike Hegel and Danto, therefore, Patočka retains the historical meaning of modern and contemporary art. His conception of the history of art, summed up under the idea of aletheia, has greater explanatory potential than Hegel’s and Danto’s conceptions, and it retains the historical meaning of modern and contemporary art. (shrink)

Rollback arguments focus on long sequences of actions with identical initial conditions in order to explicate the luck problem that indeterminism poses for libertarian free will theories (i.e. the problem that indeterministic actions appear arbitrary in a free-will undermining way). In this paper, I propose a rollback argument for probability incompatibilism, i.e. for the thesis that free will is incompatible with all world-states being governed by objective probabilities. Other than the most prominently discussed rollback arguments, this argument explicitly focusses on (...) the ability to act otherwise. It argues that the negligible probability of the relative frequencies in overall rollback patterns being relevantly different indicates that even the ability to act otherwise with regard to individual actions is not free-will enabling. My proposed argument provides probability incompatibilists with a tool to argue against a classical event-causal response to the luck problem, while it can still motivate an agent-causal response to it. (shrink)

The subject of the first section is Carnapian modal logic. One of the things I will do there is to prove that certain description principles, viz. the ''self-predication principles'', i.e. the principles according to which a descriptive term satisfies its own descriptive condition, are theorems and that others are not. The second section will be devoted to Carnapian modal arithmetic. I will prove that, if the arithmetical theory contains the standard weak principle of induction, modal truth collapses to truth. Then (...) I will propose a different formulation of Carnapian modal arithmetic and establish that it is free of collapse. Noteworthy is that one can retain the standard strong principle of induction. I will occupy myself in the third section with Carnapian epistemic logic and arithmetic. Here too it is claimed that the standard weak principle of induction is invalid and that the alternative principle is valid. In the fourth and last section I will get back to the self-predication principles and I will point to some of the consequences if one adds them to Carnapian Epistemic arithmetic. The interaction of self-predication principles and the strong principle of induction results in a collapse of de re knowability. (shrink)

This article is about an intervention or approach in mental health care that has been developed from hermeneutics, more specifically the hermeneutics of Ricoeur. In this intervention photography is used as a means to assist patients in a process of meaning making from experiences in their life world. It aims at empowerment and strengthening the agency of patients. It does so by facilitating storytelling. Mimesis, as interpreted by Ricoeur, was found to be a central concept with which we could explain (...) the therapeutic working of the approach and legitimize its ethical claims of empowerment and recovery. Another aspect is the concordance between narrative and action, as described by Ricoeur, which has a pendant in the goal orientation of the photography intervention. At the same time demonstrations and experiences from professional practice (nurses applying the intervention) will give us feedback on the theory and enrich it with new insights, e.g. on ‘iconic representation’. (shrink)

in a nervous system of a given species. This chapter provides a critical perspective on the role of connectomes in neuroscientific practice and asks how the connectomic approach fits into a larger context in which network thinking permeates technology, infrastructure, social life, and the economy. In the first part of this chapter, we argue that, seen from the perspective of ongoing research, the notion of connectomes as “complete descriptions” is misguided. Our argument combines Rachel Ankeny’s analysis of neuroanatomical wiring diagrams (...) as “descriptive models” with Hans-Joerg Rheinberger’s notion of “epistemic objects,” i.e., targets of research that are still partially unknown. Combining these aspects we conclude that connectomes are constitutively epistemic objects: there just is no way to turn them into permanent and complete technical standards because the possibilities to map connection properties under different modeling assumptions are potentially inexhaustible. In the second part of the chapter, we use this understanding of connectomes as constitutively epistemic objects in order to critically assess the historical and political dimensions of current neuroscientific research. We argue that connectomics shows how the notion of the “brain as a network” has become the dominant metaphor of contemporary brain research. We further point out that this metaphor shares (potentially problematic) affinities to the form of contemporary “network societies.” We close by pointing out how the relation between connectomes and networks in society could be used in a more fruitful manner. (shrink)

There have been attempts to get some logic out of belief dynamics, i.e. attempts to define the constants of propositional logic in terms of functions from sets of beliefs to sets of beliefs. It is interesting to see whether something similar can be done for ontological categories, i.e. ontological constants. The theory presented here will be a (modest) expansion of belief dynamics: it will not only incorporate beliefs, but also parts of beliefs, so called belief fragments. On the basis of (...) this we will give a belief-dynamical account of the ontological categories of states of affairs, individuals, properties of arbitrary adicities and properties of arbitrary orders. (shrink)

Causal Modeling Semantics (CMS, e.g., Galles and Pearl 1998; Pearl 2000; Halpern 2000) is a powerful framework for evaluating counterfactuals whose antecedent is a conjunction of atomic formulas. We extend CMS to an evaluation of the probability of counterfactuals with disjunctive antecedents, and more generally, to counterfactuals whose antecedent is an arbitrary Boolean combination of atomic formulas. Our main idea is to assign a probability to a counterfactual (A ∨ B) > C at a causal model M as a weighted (...) average of the probability of C in those submodels that truthmake A∨ B (Briggs 2012; Fine 2016, 2017). The weights of the submodels are given by the inverse distance to the original model M, based on a distance metric proposed by Eva, Stern, and Hartmann (2019). Apart from solving a major problem in the epistemology of counterfactuals, our paper shows how work in semantics, causal inference and formal epistemology can be fruitfully combined. (shrink)

Arnošt Kolman (1892–1979) was a Czech mathematician, philosopher and Communist official. In this paper, we would like to look at Kolman’s arguments against logical positivism which revolve around the notion of the fetishization of mathematics. Kolman derives his notion of fetishism from Marx’s conception of commodity fetishism. Kolman is aiming to show the fact that an entity (system, structure, logical construction) acquires besides its real existence another formal existence. Fetishism means the fantastic detachment of the physical characteristics of real things (...) or phenomena from these things. We identify Kolman’s two main arguments against logical positivism. In the first argument, Kolman applied Lenin’s arguments against Mach’s empiricism-criticism onto Russell’s neutral monism, i.e. mathematical fetishism is internally related to political conservativism. Kolman’s second main argument is that logical and mathematical fetishes are epistemologically deprived of any historical and dynamic dimension. In the final parts of our paper we place Kolman’s thinking into the context of his time, and furthermore we identify some tenets of mathematical fetishism appearing in Alain Badiou’s mathematical ontology today. (shrink)

According to epistemic reductionism about practical reasons, facts about practical reasons can be reduced to facts about evidence for ought-judgements. We argue that this view misconstrues practical conflicts. At least some conflicts between practical reasons put us in a position to know that an action ϕ is optional, i.e. that we neither ought to perform nor ought to refrain from performing the action. By understanding conflicts of practical reasons as conflicts of evidence about what one ought to do, epistemic reductionism (...) fails to account for this. In conflict cases in which ϕ-ing is optional, epistemic reductionism suggests that we have equally strong evidence for and against assuming that we ought to ϕ, and thus cannot be in a position to know that it is not the case that we ought to ϕ. This is a serious flaw. (shrink)

Katerina Kolozova is a Macedonian philosopher whose publications from last two decades aim to analyze various topics using François Laruelle’s “non-philosophy” or “non-standard philosophy.” Non-philosophy could be roughly described as radicalized deconstruction: Laruelle claims that not everything can be grasped by a philosophy: for Laruelle, “philosophy is too serious an affair to be left to the philosophers alone.”1 Non-philosophy opposes the “principle of sufficient philosophy” through which philosophy determines and decides what is real. According to Laruelle, the ultimate limit of (...) philosophical thought and its self-proclaimed sufficiency lies in its inherent tendency to close itself in a transcendental system of autofetishist conceptions, which presume that one can grasp the Real (“The Real is neither capable of being known or even ‘thought,’ but can be described in axioms. [...] Even ‘immanence’ only serves to name the Real which tolerates nothing but axiomatic descriptions or formulations.”) by a philosophical thought, or that the Real could be mediated only through human thought. Laruelle criticizes this tendency of philosophy, which is usually expressing itself through the structure of “philosophical Decision.” (“To philosophize is to decide Reality and the thoughts that result from this, i.e. to believe to be able to order them in the universal order of the Principle of Reason [Logos].”) Katerina Kolozova use Laruelle’s non-philosophy to explore more explicitly political topics. In the Cut Of Th e Real (2014), she criticized certain dogmatism of poststructuralist philosophy and feminist theory, namely their symptomatic rejection of the Real and the One. In Toward a Radical Metaphysics of Socialism (2015) and The Lived Revolution (2016) Kolozova presented a rereading of Marx, whose work she found relevant for the critique of speculative philosophical dimension of the capitalist economy, embodied in the 2008 global finance crisis, and in the latter book, she explored the possibility of a new political solidarity, based on “bodies in pain.” Kolozova doesn’t call to philosophically reconstruct Marx’s thought for the current situation, but she goes back to Marx with the help of Laruelle’s non-Marxism, contrary to the usual approach of Marxist philosophers, who often try to create certain philosophical system of Marx’s work. Together with Eileen A. Joy, Kolozova edited the anthology After the “Speculative Turn” (2016), which addressed recent realist and materialist tendencies in feminist philosophy. In her most recent book, Capitalism’s Holocaust of Animals (2019), Kolozova aimed to explore broader philosophical foundations of neoliberal capitalism, and its dealing with nonhuman animals and their suffering. According to Kolozova, “We have to start by coming to terms with what we did to the animals in the constitutive act of philosophy and via proxy to all those dehumanised that belong to the species of man ‘by courtesy’ only.” . (shrink)

[This paper is written in Czech language.] The aim of the article is to re-evaluate the still-surviving anthropological trope which, in reaction to an inquiry into the essence of man, compares humans with animals and points to culture as the means by which humans complete their “deficient” nature. This motif contrasting humans with animals has been extended by A. Gehlen who characterises humans as “beings of deficiencies”. In his view, the morphological-instinctive insufficiency of the human being must be stabilised by (...) cultural institutions, i.e. complexes of habitual actions. Merleau-Ponty, however, demonstrates that bodily beings always relate to their environment in an indirect way, on the basis of certain “standards” and “norms” of interaction, which exist by way of institution. The anthropological trope confronting humans and animals thus cannot produce, as in Gehlen, a contrast between an allegedly “direct” relationship to the world in animals, and a supposedly “indirect” relationship to the world in humans. It can be meaningfully retained only if it is interpreted in a Merleau-Pontyan way, that is, as an invitation to understand the transformation of the norms of indirect interaction with the world found in animals into those found in people, that is, if viewed as a comparison of their respective institutions. (shrink)

Indicative conditionals and tendency causal claims are closely related (e.g., Frosch and Byrne, 2012), but despite these connections, they are usually studied separately. A unifying framework could consist in their dependence on probabilistic factors such as high conditional probability and statistical relevance (e.g., Adams, 1975; Eells, 1991; Douven, 2008, 2015). This paper presents a comparative empirical study on differences between judgments on tendency causal claims and indicative conditionals, how these judgments are driven by probabilistic factors, and how these factors differ (...) in their predictive power for both causal and conditional claims. (shrink)

Collected and edited by Noah Levin -/- Table of Contents: -/- UNIT ONE: INTRODUCTION TO CONTEMPORARY ETHICS: TECHNOLOGY, AFFIRMATIVE ACTION, AND IMMIGRATION 1 The “Trolley Problem” and Self-Driving Cars: Your Car’s Moral Settings (Noah Levin) 2 What is Ethics and What Makes Something a Problem for Morality? (David Svolba) 3 Letter from the Birmingham City Jail (Martin Luther King, Jr) 4 A Defense of Affirmative Action (Noah Levin) 5 The Moral Issues of Immigration (B.M. Wooldridge) 6 The Ethics of our (...) Digital Selves (Noah Levin) -/- UNIT TWO: TORTURE, DEATH, AND THE “GREATER GOOD” 7 The Ethics of Torture (Martine Berenpas) 8 What Moral Obligations do we have (or not have) to Impoverished Peoples? (B.M. Wooldridge) 9 Euthanasia, or Mercy Killing (Nathan Nobis) 10 An Argument Against Capital Punishment (Noah Levin) 11 Common Arguments about Abortion (Nathan Nobis & Kristina Grob) 12 Better (Philosophical) Arguments about Abortion (Nathan Nobis & Kristina Grob) -/- UNIT THREE: PERSONS, AUTONOMY, THE ENVIRONMENT, AND RIGHTS 13 Animal Rights (Eduardo Salazar) 14 John Rawls and the “Veil of Ignorance” (Ben Davies) 15 Environmental Ethics: Climate Change (Jonathan Spelman) 16 Rape, Date Rape, and the “Affirmative Consent” Law in California (Noah Levin) 17 The Ethics of Pornography: Deliberating on a Modern Harm (Eduardo Salazar) 18 The Social Contract (Thomas Hobbes) -/- UNIT FOUR: HAPPINESS 19 Is Pleasure all that Matters? Thoughts on the “Experience Machine” (Prabhpal Singh) 20 Utilitarianism (J.S. Mill) 21 Utilitarianism: Pros and Cons (B.M. Wooldridge) 22 Existentialism, Genetic Engineering, and the Meaning of Life: The Fifths (Noah Levin) 23 The Solitude of the Self (Elizabeth Cady Stanton) 24 Game Theory, the Nash Equilibrium, and the Prisoner’s Dilemma (Douglas E. Hill) -/- UNIT FIVE: RELIGION, LAW, AND ABSOLUTE MORALITY 25 The Myth of Gyges and The Crito (Plato) 26 God, Morality, and Religion (Kristin Seemuth Whaley) 27 The Categorical Imperative (Immanuel Kant) 28 The Virtues (Aristotle) 29 Beyond Good and Evil (Friedrich Nietzsche) 30 Other Moral Theories: Subjectivism, Relativism, Emotivism, Intuitionism, etc. (Jan F. Jacko). (shrink)

The study of biodiversity spans many disciplines and includes data pertaining to species distributions and abundances, genetic sequences, trait measurements, and ecological niches, complemented by information on collection and measurement protocols. A review of the current landscape of metadata standards and ontologies in biodiversity science suggests that existing standards such as the Darwin Core terminology are inadequate for describing biodiversity data in a semantically meaningful and computationally useful way. Existing ontologies, such as the Gene Ontology and others in the Open (...) Biological and Biomedical Ontologies (OBO) Foundry library, provide a semantic structure but lack many of the necessary terms to describe biodiversity data in all its dimensions. In this paper, we describe the motivation for and ongoing development of a new Biological Collections Ontology, the Environment Ontology, and the Population and Community Ontology. These ontologies share the aim of improving data aggregation and integration across the biodiversity domain and can be used to describe physical samples and sampling processes (for example, collection, extraction, and preservation techniques), as well as biodiversity observations that involve no physical sampling. Together they encompass studies of: 1) individual organisms, including voucher specimens from ecological studies and museum specimens, 2) bulk or environmental samples (e.g., gut contents, soil, water) that include DNA, other molecules, and potentially many organisms, especially microbes, and 3) survey-based ecological observations. We discuss how these ontologies can be applied to biodiversity use cases that span genetic, organismal, and ecosystem levels of organization. We argue that if adopted as a standard and rigorously applied and enriched by the biodiversity community, these ontologies would significantly reduce barriers to data discovery, integration, and exchange among biodiversity resources and researchers. (shrink)

It is generally thought that suspension of judgment about a proposition p is the doxastic attitude one is rationally compelled to adopt whenever the epistemic reasons for and against p are equipollent or equally credible, that is, whenever the total body of available evidence bearing on p epistemically justifies neither belief nor disbelief in p. However, in a recent contribution to this journal, Jan Wieland proposes “to broaden the conditions for suspension, and argue that it is rational to suspend belief (...) on a certain issue even if one’s current evidence is not neutral (or even close to neutral)”. My aim in this paper is to point to a number of problems in Wieland’s position, some of which in connection with the account of Pyrrhonian skepticism found in the extant works of Sextus Empiricus. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE OS TRANSTORNOS DO CICLO ESTRAL DE VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__6. Transtornos do ciclo estral -/- Qualquer alteração na frequência, duração ou intensidade do ciclo estral é considerada uma perturbação do ciclo, cujas origens variam etiologicamente. As perturbações do ciclo podem originar-se em qualquer das partes do eixo hipotálamo-hipófise-ovário (FRAZER, 2005; GORDON, 1996). Pode ou não ser do tipo (...) permanente e pode depender de sua origem, momento e intensidade cursar com outras alterações reprodutivas, por exemplo uma retenção do corpo lúteo, dá lugar a prolongamento da fase lútea, altos níveis de progesterona circulante e pode, finalmente, desencadear em um cisto luteal ou em uma metrite. Entre os fatores desencadeadores da falha do ciclo estral estão os fatores de origem nutricional, dentre eles: 6.1 Minerais 6.1.1 Relação Na:K (Sódio: Potássio) A deficiência de sódio pode causar distúrbios do ciclo estral, isto porque as células animais intracelularmente possuem uma alta concentração de K e uma baixa concentração de Na, esta relação pode chegar a 10:1 ou mais, em relação ao meio externo. Com esta relação, as concentrações intracelulares estão em equilíbrio com o meio externo. A absorção e secreção de cátions pela célula para conseguir o equilíbrio é simultânea, gerada por um sistema de transporte específico chamado "bomba Na-K". Se a nível celular não existe um balanço iônico de K:Na, a maior prioridade das células tubulares do rim é a de conseguir novamente um equilíbrio, o mecanismo destas células é o da reabsorção do íon que se encontre em excesso de água, diminuindo a quantidade deste no líquido para manter as funções em equilíbrio dinâmico. Os desequilíbrios não compensados a nível celular ou renal, levam a alterações na condutividade nervosa por alteração da bomba de transmissão elétrica. O ciclo estral é alterado por diminuir a expressividade dos sinais comportamentais de estro, que são produzidos por concentrações crescentes de estrogênio mas com alta necessidade de adequação nervosa para a exposição corporal do cio e a aceitação da monta. O potássio, em particular, desempenha um papel fundamental como coator em certas interações enzimáticas, incluindo a transferência de energia, a síntese de proteínas e o metabolismo de hidratos de carbono, em especial nos sistemas em que o ADP está envolvido, as hexoquinases e a anidrase carbônica. O sódio, por sua vez, é o principal cátion extracelular, regula o equilíbrio hídrico no organismo e a mecânica de fluidos, desta forma regula a pressão osmótica e a troca aquosa nos tecidos. Devido a esta função, um dos fatores importantes do fluxo Na:K é o rim, que é controlado pela aldosterona, a principal hormona reguladora da absorção de sódio e excreção de potássio. Qualquer desequilíbrio na relação Na:K, afetará o ciclo estral, de maneira direta e indireta, através da alteração na síntese de proteínas e da perda da regulação hídrica, fator importante pelas secreções que devem acompanhar as manifestações de cio/estro. 6.1.2 Relação Cobalto (Co) A deficiência de cobalto gera um efeito biológico determinado pela sua presença na molécula da vitamina B12, a qual regula a hematopoese (Ativa a síntese de protoporfirina) e afeta o metabolismo do nitrogênio e dos carboidratos. A vitamina B12 atua como uma coenzima da transmetilação (síntese do glutamato mutase, metilmalonil-CoA-Mutase, diol-dehidratase e redução dos ribonucleótidos a desoxirribonucleótidos, isomerização da a-lisina, etc.). Especialmente em ruminantes, a reação mutase da metilmalonina-CoA está relacionada com o metabolismo do ácido propiônico e, portanto, com a síntese de glicose e o equilíbrio energético. O cobalto também está envolvido na carboxilação da propionil-CoA à metilmalonil-CoA e na isomerização deste último para succinil-CoA. O metabolismo do ácido propiônico ocorre no fígado e é reduzido pelo fato do metilmalonil não poder ser convertido em succinil-CoA, impedindo a sua passagem para oxalacetato e glicose, gerando uma relação inversa entre os níveis de energia e proteína; causando uma diminuição de GnRH que afeta negativamente a liberação de LH que, por sua vez, cria um aumento na FSH. Isso produz uma anulação da ovulação e, consequentemente, ausência de um ciclo estral verdadeiro. Vale reforçar que, para prevenção da deficiência do cobalto, o criador pode optar pelo fornecimento de volumosos que dispõem de quantidades de cobalto que suprem as exigências dos animais, ou pela inserção de sais de cobalto à mistura da ração, sempre no intervalo sugerido de 0,07 e 0,11 mg/kg para cada animal, suprindo a necessidade do mesmo e garantindo assim a prevenção dos transtornos do ciclo estral ou outras afecções do sistema reprodutivo. 6.1.3 Relação Cobre (Cu) e Molibdênio (Mo) A deficiência de cobre gera, indiretamente, molibdênio, durante esse processo, tanto o macho como a fêmea são inférteis ou sub-férteis, mas, em geral, os transtornos surgem não por molibdeniose mas por hipocuprose condicionada por excesso de molibdênio nas pastagens e pelos sulfatos presentes na água de bebida (BREM, 2016). Isso leva à formação de tiomolibdato no rúmen, que por sua vez combina com o cobre para formar tiomolibdato de cobre, sal muito insolúvel. O tiomolibdato presente, formado em excesso e que não encontra cobre suficiente, contribuirá para produzir a diarreia, limitando ainda mais a absorção de cobre. A interferência mais importante do molibdênio ocorre no processo metabólico do cobre, interferindo sua atividade enzimática. O molibdênio atua sobre o complexo sulfeto-oxidase hepático. A enzima que está envolvida na oxidação de metabolitos sulfurados, reduz a sua atividade na presença de altos teores de molibdênio, especialmente quando a quantidade de cobre é baixa. Daqui resulta a formação de sulfureto de cobre, muito insolúvel e, portanto, pouco ou nada utilizável pelas células e/ou tecidos (QUIROZ-ROCHA & BOUDA, 2001). O excesso de molibdênio nas pastagens ou na água de bebida reduz a quantidade de cobre no fígado, mas para uma dada dose de molibdênio, esta redução é diretamente proporcional ao aumento dos sulfatos na ingestão, porque só na presença de sulfatos o molibdênio exerce sua ação limitante. O melhor modo de tratar o molibdênio e a ação dos sulfatos sobre o cobre, é aumentar a quantidade de cobre disponível pelos animais, seja por via bucal ou parenteral. Desta forma, há aumentos na cupremia e no ganho de peso. É conveniente, para o efeito, efetuar um controle dos resultados mediante a observação clínica, pesagem dos animais e análise de cobre no sangue. Isso permitirá estabelecer as doses ideais e adequadas para cada estabelecimento e efetuar um estudo econômico da suplementação (BAVERA, 2002). Como já foi tratado o requerimento do cobre para evitar os problemas reprodutivos das vacas, falemos do molibdênio (Mo). O Mo é um elemento primordial para bovinos leiteiros, uma vez que é componente de uma enzima presente no leite (xantina oxidasse). A deficiência de Mo a nível prático não foi relatada, porém casos podem acontecer. Para ovinos, que é uma espécie ruminante, a concentração exigida pelo animal em Mo presente na MS é de 5 a 10 mg/kg, porém deve levar em consideração a relação crítica entre o Mo e o Cu que deve ser no máximo 20 e nunca superior. O nível crítico de toxidade de Mo nos alimentos volumosos (forrageiras, gramíneas e leguminosas) não pode ultrapassar os 6% por kg de MS. Através de todos esses cuidados, o criador poderá obter sucesso tanto na prevenção contra os distúrbios do ciclo estral das vacas, quanto de outras complicações como toxidade, desnutrição, etc. 6.2 Relação energia:proteína Em relação ao aumento do consumo de proteína crua ou de deficiência de energia, aumenta-se a quantidade de ureia no sangue e produz-se uma toxicidade tecidular, afetando o endométrio e diminuindo a produção de prostaglandinas, que são as encarregadas de manter o corpo lúteo, caso não se mantenha acaba provocando um ciclo estral longo. A situação pode ser explicada a nível do eixo hipotálamo-hipófise, no qual os baixos níveis de glicose inibem a secreção de GnRH e resultam na diminuição da pulsatilidade da LH, seja por ação direta ou mediada através das ß-endorfinas. Outro fator que afeta o crescimento folicular é a nutrição, especificamente a perda da condição corporal, quando o animal não se alimenta direito ou quando se alimenta não tem uma condição balanceada que supra suas exigências nutricionais e que tenha um aceitável ganho de peso diário (GPD), acaba perdendo massa muscular ou de gordura, em outras palavras altera-se a condição corporal do mesmo, e se a perda for de 22 a 24 % de peso corporal (PC), os animais que perdem essa condição entram em anestro o que acaba tornando um animal inviável para a reprodução e também para o abate, uma vez que encontra-se fora do peso ideal. Tanto as proteínas quanto a energia foram tratados em trabalhos anteriores, porém nunca é tarde para salientar que ambas devem ser fornecidas em qualidade e quantidade que consiga favorecer ao desenvolvimento do animal e aos mecanismos fisiológicos do mesmo. 6.3 Fito-toxidade Finalmente, um fator adicional que induz a alteração da ciclicidade estral são os fitoestrógenos, plantas com altos teores de isoflavonas que possuem, no organismo animal, uma ação estrogênica. Os fitoestrógenos estão amplamente difundidos, nos trevos, alfafa, milho e nas pastagens de cultivo intensivo. Os fitoestrogênios são diferentes dos estrogênios produzidos pelo animal, mas a sua ação é idêntica nos receptores do trato reprodutivo; o seu metabolismo e excreção é diferente (por exemplo, desmetilização) e a sua excreção renal através dos glicoronosidos, assim mesmo a formação de ésteres sulfatos no tecido hepático é menor, acumulando-se em circulação e alterando a duração da fase estrogênica do ciclo, isso leva à ninfomania das vacas e com ela a perda da função reprodutiva. Deve-se estar atento ao pasto que se cultiva e ao solo em que se implanta o pasto, uma vez que o solo pode ter excessos de minerais prejudiciais ao animal e que o coloque em uma situação de toxidade, já que a planta absorve do solo o excesso e da planta vai para o animal por meio direto ou pela silagem. Um exemplo é o teor de molibdênio na planta que não pode ser maior que 6%, se for ocorrerá inúmeras transformações fisiológicas maléficas ao animal, que acabará sendo descartado do objetivo que seria a reprodução na fazenda. -/- Apoio -/- Realização -/- REFERÊNCIAS BIBLIOGRÁFICAS BAVERA, Guillermo Alejandro. Aguas y aguadas para el ganado. Rio Cuarto: Inter-Medica Editorial, 2009. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. BREM, J. J. et al. Alteraciones del ciclo estral provocadas por un alto ingreso de molibdeno en vaquillonas Brangus y respuesta a la suplementación con cobre. Revista Veterinaria, v. 12, n. 1 y 2, p. 28-33, 2016. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. GRAHAM, Thomas W. Trace element deficiencies in cattle. Veterinary clinics of North America: food animal practice, v. 7, n. 1, p. 153-215, 1991. GUEDES, Luciana Freitas et al. A importância do cobre, molibdênio e enxofre na alimentação de ovinos. Nucleus Animalium, v. 10, n. 2, p. 7-22, 2018. HURLEY, W. L.; DOANE, R. M. Recent developments in the roles of vitamins and minerals in reproduction. Journal of Dairy Science, v. 72, n. 3, p. 784-804, 1989. KUMAR, Sudhir et al. Importance of micro minerals in reproductive performance of livestock. Veterinary world, v. 4, n. 5, p. 230, 2011. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. MILLS, C. F. Cobalt deficiency and cobalt requirements of ruminants. Recent advances in animal nutrition, p. 129-141, 1981. NICODEMO, M. L. F.; SERENO, J. R. B.; AMARAL, T. B. Minerais na eficiência reprodutiva de bovinos. Embrapa Pecuária Sudeste-Documentos (INFOTECA-E), São Carlos, 2008. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. QUIROZ-ROCHA, Gerardo F.; BOUDA, Jan. Fisiopatología de las deficiencias de cobre en rumiantes y su diagnóstico. Vet. Méx, v. 32, n. 4, p. 289, 2001. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. YASOTHAI, R. Importance of minerals on reproduction in dairy cattle. International Journal of Science, Environment and Technology, v. 3, n. 6, p. 2051-2057, 2014. Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE OS CIOS OU ESTROS SILENCIOSOS EM VACAS E. I. C. da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim Departamento de Zootecnia – UFRPE sede CIOS OU ESTROS SILENCIOSOS EM BOVINOS INTRODUÇÃO Um cio ou "estro silencioso" ocorre quando as mudanças ováricas são normais, mesmo com ovulação, mas não há comportamento estral. Isso não deve ser confundido com um estro não observado devido a falha na detecção do mesmo. A ocorrência do cio ou "estro (...) silencioso" é mais frequente durante o primeiro e segundo ciclo pós-parto (25 a 40 dias pós-parto). O acesso ao comportamento de atividade estral geralmente é gradual e ocorre em várias horas. Assim, a intensidade do estro e o padrão típico de comportamento em uma determinada vaca, variará do começo ao fim do mesmo. O conhecimento dessas mudanças graduais do estro servem como sinais e podem ser usados pelo produtor para indicar se uma vaca está manifestando o início ou a finalização do estro. (FRAZER, 2005; GORDON, 1996). O fracasso da detecção do estro é o problema mais sério e generalizado que afeta a eficácia do serviço nas vacas. Vários fatores de manejo contribuem para o fracasso no diagnóstico do estro, mas a incapacidade de reconhecer os sinais do estro é uma causa comum. A detecção do estro é necessária para um programa de inseminação das vacas leiteiras e é a chave do uso bem sucedido da inseminação artificial (AI) (THATCHER et al., 2006). As temperaturas ambientes quentes ou muito frias reduzem o comprimento dos períodos estrais em algumas vacas, e incrementam as dificuldades na detecção do estro. Quando a vaca manifesta o estro, exibe padrões de comportamento que são distintamente diferenciados do descanso do ciclo estral. Relaciona-se com o estro, o maior desenvolvimento folicular ovárico e a descarga reforçada de estrogênio. O estrogênio, hormônio sexual do ovário, atua na vaca causando a indução do comportamento estral. Cios/estros silenciosos podem ser difíceis de se manifestarem na vaca, uma vez que torna-se muito difícil não observar uma vaca, que mesmo tendo um cio silencioso, aceitando a monta ou montando em outras, o muco que escorre pela vulva, o comportamento de micção frequente, etc. Vários fatores podem ocasionar essa manifestação ociosa do cio, porém a mais relevante é a nutricional, em especial com a deficiência ou exagero de minerais essenciais e intimamente relacionados com a reprodução. 9.1 Minerais 9.1.1 Fósforo (P) Dentro das deficiências minerais, o baixo nível de fósforo afeta os mecanismos energéticos relacionados com as manifestações corporais do cio. Os hábitos de comportamento típico de montar e deixar-se montar, o evento de caminhadas errantes em busca de companheiros sexuais unido ao baixo consumo de alimento durante as horas de estro, leva a atentar que, sob condições de deficiência mineral de fósforo, o animal não mostre seu comportamento sexual esperado, já que outros processos fisiológicos, todos relacionados com as funções autônomas, devem ser favorecidos. Sempre enfatizando a prevenção por afecções relacionadas aos minerais que possuem relação direta com a fertilidade e reprodução dos bovinos, a suplementação do P pode ocorrer de diversas maneiras, dentre elas o fornecimento de 1,43 mg/kg de MS do mineral na dieta dos animais, tendo uma taxa percentual de 0,17 a 0,59% de P presente em kg/MS para todas as categorias animais, o que previne ou combaterá quaisquer anomalias que viera a acometer o rebanho. A administração dessa quantidade pode ocorrer em sistemas de fornecimento via SMI (suplementação mineral injetável), via água, forragens ou via ração. 9.1.2 Manganês (Mn) A maioria dos efeitos de deficiência do Mn deve-se à sua função na síntese de muco polissacarídeo, estes são imprescindíveis na matriz orgânica dos ossos e dos dentes. Outra função do Mn é a participação nos processos de oxido-redução, respiração tecidular, formação do osso, reprodução e funções endócrinas. Os bovinos que têm uma baixa ingestão de manganês nas suas dietas podem ter uma puberdade tardia, baixas porcentagens de gravidez, uma acentuada tendência aos abortos e bezerros fracos ao nascer. Como sempre falado, todos os minerais são essenciais para a manutenção e normalidade do corpo e dos mecanismos fisiológicos do mesmo, logo, como o Mn não é diferente, sua participação na dieta do animal deve obedecer os 40 mg/kg de MS e nunca superior a 1000 ppm, as concentrações desse mineral são mais abundantes em forragens e sua via de suplementação pode ser através da ração balanceada com todas as quantidades estabelecidas de macro e micro minerais ou através do sistema SMI. 9.1.3 Cobre (Cu) Outro mineral relacionado com o cio ou estro silencioso é o cobre. As vacas que consomem pastos deficientes em cobre podem apresentar uma infertilidade associada a cios atrasados ou suprimidos, falhas na nidificação, reabsorções embrionárias e transtornos na espermatogênese nos machos. Os bovinos que consomem pastagens contendo menos que 3 mg Cu/kg MS por dia apresentam sinais de deficiência. As desordens reprodutivas relacionadas com o cobre (Cu) podem estar relacionadas a uma deficiência, bem como a uma interferência na sua utilização. A disponibilidade desse elemento pode ser reduzida pelo excesso de outros, como exemplo o molibdênio, enxofre, ferro, cálcio, zinco e cádmio (QUIROZ-ROCHA & BOUDA, 2001; KINCAID, 1999). O Cu é um elemento primordial como outro qualquer, sendo assim, sua administração aos animais deve obedecer aos parâmetros estabelecidos por instituições de pesquisa agropecuária que ditam um fornecimento de Cu entre 10-18 mg/kg de MS para todas as categorias animais. A via de suplementação do cobre pode ser diversa, mas as mais aceitas são pelas forragens, pelo sistema SMI ou através do concentrado balanceado industrial. O excesso de Cu gera Mo, e a relação entre ambos não deve ser superior à 20. Por fim, em geral, cio/estro silencioso se apresentará em deficiências de energia pelos altos requerimentos desta durante o período do mesmo, e quando se apresentam os desequilíbrios eletrolíticos, uma vez que a homeostase básica faz com que os processos de regulação bioquímica sejam prioritários para o indivíduo, ainda sobrepondo suas necessidades reprodutivas. REFERÊNCIAS BIBLIOGRÁFICAS BARRENHO, Gonçalo José Pinheiro. Nutrição e fertilidade em bovinos de leite. 2016. Dissertação de Mestrado. Universidade de Évora. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. DEHNING, R. Interrelaciones entre nutriión y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. DIAS, Juliano Cesar et al. Alguns aspectos da interação nutrição-reprodução em bovinos: energia, proteína, minerais e vitaminas. PUBVET, v. 4, p. Art. 738-743, 2010. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. FUCK, E. J.; MORAES, G. V.; SANTOS, G. T. Fatores nutricionais na reprodução das vacas leiteiras. I. Energia e proteína. Rev Bras Reprod Ani, v. 24, p. 147-161, 2000. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. KINCAID, R. L. Assessment of trace mineral status of ruminants: A review. In: Proceedings of the American Society of Animal Science. 1999. p. 1-10. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. QUIROZ-ROCHA, Gerardo F.; BOUDA, Jan. Fisiopatología de las deficiencias de cobre en rumiantes y su diagnóstico. Vet. Méx, v. 32, n. 4, p. 289, 2001. SARTORI, Roberto; GUARDIEIRO, Monique Mendes. Fatores nutricionais associados à reprodução da fêmea bovina. Revista Brasileira de Zootecnia, v. 39, p. 422-432, 2010. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. THATCHER, W. W. et al. Strategies for improving fertility in the modern dairy cow. Theriogenology, v. 65, n. 1, p. 30-44, 2006. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. TEIXEIRA, J. C. Nutrição de ruminantes. Lavras: FAEPE, 1992. (shrink)

The sensorimotor theory of perceptual consciousness offers a form of enactivism in that it stresses patterns of interaction instead of any alleged internal representations of the environment. But how does it relate to forms of enactivism stressing the continuity between life and mind? We shall distinguish sensorimotor enactivism, which stresses perceptual capacities themselves, from autopoietic enactivism, which claims an essential connection between experience and autopoietic processes or associated background capacities. We show how autopoiesis, autonomous agency, and affective dimensions of experience (...) may fit into sensorimotor enactivism, and we identify differences between this interpretation and autopoietic enactivism. By taking artificial consciousness as a case in point, we further sharpen the distinction between sensorimotor enactivism and autopoietic enactivism. We argue that sensorimotor enactivism forms a strong default position for an enactive account of perceptual consciousness. (shrink)

In recent years the idea that perceptual content is tensed in the sense that we can perceive objects as present or as past has come under attack. In this paper the notion of tensed content is to the contrary defended. The paper argues that assuming that something like an intentionalistic theory of perception is correct, it is very reasonable to suppose that perceptual content is tensed, and that a denial of this notion requires a denial of some intuitively very plausible (...) principles. The paper discusses some common objections against the notion of tensed content and concludes that none of them succeeds in showing that perceptual content cannot be tensed. (shrink)

Tradução para o português do ensaio "Social Morality and Individual Ideal”. Publicado originalmente em Philosophy: The Journal of the Royal Institute of Philosophy, vol. XXXVI, n. 136, p. 1-17, Jan. 1961. Republicado em: STRAWSON, P. F. Freedom and Resentment and Other Essays. Londres: Methuen, 1974. [Routledge, 2008, p. 26-44]. ]. Publicado na coletânea: Ensaios sobre a filosofia de Strawson: com a tradução de Liberdade e ressentimento & Moralidade social e ideal individual. Organizadores: Jaimir Conte & Itamar Luís Gelain. Editora da (...) UFSC, 2015. ISBN: 9788532807250. (shrink)

This paper is a defense of an internalist view of the perception of shapes. A basic assumption of the paper is that perceptual experiences have certain parts which account both for the phenomenal character associated with perceiving shapes—phenomenal shapes—and for the intentional content presenting shapes—intentional shapes. Internalism about perceptions of shapes is defined as the claim that phenomenal shapes determine the intentional shapes. Externalism is defined as the claim that perceptual experiences represent whatever shape the phenomenal shape reliably tracks. The (...) argument against externalism proceeds in three steps. First, it is argued that phenomenal shapes are modality specific, such that a phenomenal shape that features in a visual perceptual experience cannot feature in a haptic perceptual experience, and vice versa. Second, it is argued that intentional shapes are amodal. Third, it is argued that externalism is incompatible with the fact that phenomenal shapes are modality specific and intentional shapes amodal. (shrink)

This paper clarifies Merleau-Ponty’s original account of “higher-order” cognition as fundamentally embodied and enacted. Merleau-Ponty’s philosophy inspired theories that deemphasize overlaps between conceptual knowledge and motor intentionality or, on the contrary, focus exclusively on abstract thought. In contrast, this paper explores the link between Merleau-Ponty’s account of motor intentionality and his interpretations of our capacity to understand and interact productively with cultural symbolic systems. I develop my interpretation based on Merleau-Ponty’s analysis of two neuropathological modifications of motor intentionality, the case (...) of the brain-injured war veteran Schneider, and a neurological disorder known as Gerstmann’s syndrome. Building on my analysis of Schneider’s sensorimotor compensatory performances in relation to his limitations in the domains of algebra, geometry, and language usage, I demonstrate a strong continuity between the sense of embodiment and enaction at all these levels. Based on Merleau-Ponty’s interpretations, I argue that “higher-order” cognition is impaired in Schneider insofar as his injury limits his sensorimotor capacity to dynamically produce comparatively more complex differentiations of any given phenomenal structure. I then show how Merleau-Ponty develops and specifies his interpretation of Schneider’s intellectual difficulties in relation to the ambiguous role of the body, and in particular the hand, in Gerstmann’s syndrome. I explain how Merleau-Ponty defends the idea that sensorimotor and quasi-representational cognition are mutually irreducible, while maintaining that symbol-based cognition is a fundamentally enactive and embodied process. (shrink)

The topic of this paper is the perception of properties. It is argued that the perception of properties allows for a distinction between the sense of the identity and the sense of the qualitative nature of a property. So, for example, we might perceive a property as being identical over time even though it is presented as more and more determinate. Thus, you might see an object first as red and then as crimson red. In this case, the property is (...) perceived as identical over time, even though the sense of the qualitative nature (the redness, the crimson redness) of the property is changing. The distinction between the sense of identity and the sense of quality is explicated in terms of perceiving a particular property, a trope, and perceiving it as an instance of a universal. It is subsequently argued that the perceived tropes cannot constitute the phenomenal character of the perceptual experience. (shrink)

In view of the philosophical problems that vex the debate on situated affectivity, it can seem wise to focus on simple cases. Accordingly, theorists often single out scenarios in which an individual employs a device in order to enhance their emotional experience, or to achieve new kinds of experience altogether, such as playing an instrument, going to the movies or sporting a fancy handbag. I argue that this narrow focus on cases that fit a ‘user/resource model’ tends to channel attention (...) away from more complex and also more problematic instances of situated affectivity. Among these are scenarios in which a social domain draws individuals into certain modes of affective interaction, often by way of attunement and habituation to affective styles and interaction patterns that are normative in the domain in question. This can lead to a phenomenon that is not so much ‘mind extension’ than ‘mind invasion’: affectivity is dynamically framed and modulated from without, often contrary to the prior orientations of the individuals in question. As an example, I discuss affective patterns prevalent in today’s corporate workplace. I claim that workplace affect sometimes contributes to what is effectively a ‘hack’ of employees’ subjectivity. (shrink)

The pragmatic theory of explanation is an attempt to see explanation as a linguistic response to a cognitive problem where the content of the response depends on the context of the scientific inquiry. The present paper draws on the rhetorical situation, as it is defined by Loyld Bitzer, in order to understand how the context may influence the content as well as the acceptability of the response.